Our societies are becoming more and more digital. Data is now the basic resources enabling more personalised, predictive, preventive and participatory care. But massive platforms, called "gatekeepers", have emerged and the control of the good use of personal data has emerged as a major challenge to address around the world. Additionally, we observe data silos and a lack of fluidity for data sharing. Between the needs for data availability to develop innovations and better services and the needs for new regulations to ensure ethics and citizens' control over their personal data, this session will explore new models of data governance proposed at all levels (continental, national, local).The SARS-CoV-2 pandemic is having a terrible impact on humanity, obviously on the health of populations (both in relation to the virus and with the associated preventive measures) but as well on the whole life and activities of human beings. The Digital transformation of health and social care has appeared as inevitable facing this situation. So the last year has been an intense period of implementation of innovations (being around for several years or newly created) such as teleconsultations, AI-powered diagnostic solutions, tracking apps and digital passport, remote monitoring and support, mental health management, etc. This session will showcase a few of these innovations which are nowadays fully part of our healthcare systems and will highlight the upcoming challenges.